Tommaso di Giovanni Cassai, better known as Masaccio (San Giovanni Valdarno, 1401- Rome, 1428), arrives very young in Florence and enters the circle of his compatriot Masolino da Panicale.

Masolino formed himself by working at the north door of the Florentine Baptistery with Ghiberti. Sensitive to the perspective revolution of the fifteenth century.

The figure of this painter who comes from Valdarno is strictly related to that of Masaccio. Mariotto was born in San Giovanni around 1395 and was brother-in-law of the great painter.

Giovanni of Ser Giovanni from Mone Cassai was Masaccio’s younger brother. He was born from Giovanni and Jacopa; surely influenced in the choice of his profession by his grandfather Mone Cassaio.

Giovanni Mannozzi, known as Giovanni da San Giovanni (San Giovanni Valdarno 1592 – Florence 1636) was considered by his contemporaries an excellent teacher and fresco painter.

Niccolò Nasoni (San Giovanni Valdarno 1691-1773) was a painter and internationally renowned architect who worked in Siena, Rome, Malta and, mainly, in Oporto, Portugal.

The priest Francesco Feroci (San Giovanni Valdarno 1673-Florence 1750), was student of Giovanni Maria Casini and his successor in the position of first organist of the Cathedral of Florence.